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Kikis, Christie, Lee, Fay and Gray Publish Study on Neurodegenerative Disease

Elise Kikis, and her students Nakeirah Christie (C’15), Amy Lee (C’16), Hannah Fay (C’15), and Amelia Gray (C’16) just published a paper in PLoS ONE, titled “Novel Polyglutamine Model Uncouples Proteotoxicity from Aging”. They describe their work of two years during which time they characterized the toxic effects of the aggregation-prone ataxin-3 protein that leads to the neurodegenerative disease known as Machado-Joseph Disease. They plan to expand on this work during the next academic year.

Their article is available here.